Around 2 a.m., a sedan was touring alongside the freeway, close to Sixth Street, when the driving force collided with the horse, in accordance with the Cal Fire Riverside County Fire Department.
One sufferer and the horse have been pronounced dead on the scene.
Another one who was within the automobile was taken to a hospital with minor accidents.
It was not instantly clear who was driving, or how the horse had made its manner onto the freeway.
The horse might have escaped from a truck that was towing the animal in a trailer, in accordance with footage from information videographer OnScene TV.
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